Fig. 1
From: Targeting the tumor microenvironment in B-cell lymphoma: challenges and opportunities
Major constituents of the TME and targeted therapies. The figure depicts the typical microenvironment of B-cell lymphoma. Tumor microenvironment refers to the internal environment in which tumor cells produce and live, major cellular and noncellular components. It includes not only the tumor cells but also the immune and inflammatory cells, fibroblasts and other cells around them. It also comprises the intercellular substance, micro-vessels and biological molecules infiltrated in the nearby area. Current strategies targeting TME components are also highlighted