Table 1 Overview of dysregulated circRNAs in hepatocellular carcinoma (HCC)

circCDYL

Up

miR-892a

miR-328-3p

HDGF/HIF1AN

Proliferation (+)

[39]

circSLC3A2

Up

miR-490-3p

PPM1F

Proliferation (+)

[40]

circFBLIM1

Up

miR-346

FBLIM1

Proliferation (+)

[41]

circHIPK3

Up

miR-124

AQP3

Proliferation (+)

[42]

circZNF566

Up

miR-4738-3p

TDO2

Proliferation (+)

[43]

circMAT2B

Up

miR-338-3p

PKM2

Proliferation (+);

Metastasis (+)

[44]

circASAP1

Up

miR-326

miR-532-5p

MAPK1

CSF-1

Proliferation (+);

Metastasis (+)

[37]

circDYNC1H1

Up

miR-140-5p

SULT2B1

Proliferation (+)

[45]

circARFGEF2

Up

miR-143-3p

PCBP1

FOSL2

CD44v6

Proliferation (+);

Metastasis (+)

[46]

circMAST1

Up

miR-1299

CTNND1

Proliferation (+)

[47]

circBACH1

Up

–

p27

HuR

Proliferation (+)

[48]

circRHOT1

Up

–

TIP60

NR2F6

Proliferation (+);

Metastasis (+)

[49]

circβ-catenin

Up

–

β-catenin-370aa

(circβ-catenin’s translation product)

Proliferation (+);

Metastasis (+)

[50]

circUHRF1

Up

miR-449c-5p

TIM-3

Proliferation (+);

Metastasis (+);

Drug resistance (+);

Immunity (−)

[51]

circSORE

Up

miR-103a-2-5p

miR-660-3p

Wnt2b

Drug resistance (+)

[52]

circSORE

Up

–

YBX1

Drug resistance (+)

[53]

circMET

Up

miR-30-5p

CXCL10

Drug resistance (+);

Immunity (−)

[54]

circUBAP2

Up

miR-194-3p

MMP9

Proliferation (+);

Metastasis (+)

[59]

circPABPC1

Down

–

ITGB1

Proliferation (−);

Metastasis (−)

[60]

circADD3

Down

–

EZH2

CDK1

Proliferation (−);

Metastasis (−)

[55]

circMTO1

Down

miR-9

P21

Proliferation (−)

[56]

circSETD3

Down

miR-421

MAPK14

Proliferation (−)

[57]

circSMARCA5

Down

miR-17-3p

miR-181b-5p

TIMP3

Proliferation (−)

[36]

circZKSCAN1

Down

–

FMRP

CCAR1

Proliferation (−);

Metastasis (−)

[58]