Table 6 Conditioning regimens for severe aplastic anemia
Conditioning Regimen | Drug | Dose(total) | Schedule(day) | Donor type |
|---|---|---|---|---|
Cy-ATG | Cy | 200 mg/kg | − 5 to − 2 | MSD/URD |
ATG | 10 mg/kg | − 5 to − 2 | ||
FluCy-ATG | Flu | 120 mg/m2 | − 5 to − 2 | URD/HID |
Cy | 90–120 mg/kg | − 3, − 2 | ||
ATG | 10 mg/kg | − 5 to − 2 | ||
Bu | 6.4 mg/kg (iv.) | − 7, − 6 | HID | |
Cy | 200 mg/kg | − 5 to − 2 | ||
ATG | 10 mg/kg | − 5 to − 2 | ||
BuFluPTCy [79] | Bu | 6.4 mg/kg (iv.) | − 8, − 7 | HID |
Flu | 200 mg/m2 | − 8 to − 4 | ||
Cy | 29 mg/kg | − 3, − 2 | ||
Cy | 120 mg/kg | + 3, + 4 |