Table 1 Baseline demographic and disease characteristics
Patients at Low Risk for TLS n = 6 | Patients at Increased Risk for TLS n = 15a | All Patients N = 21 | |
|---|---|---|---|
Median age, years (range) | 62 (54–67) | 70 (53–84) | 68 (53–84) |
Age category, years, n (%) | |||
< 60 | 2 (33) | 1 (7) | 3 (14) |
60–69 | 4 (67) | 5 (33) | 9 (43) |
≥ 70 | 0 | 9 (60) | 9 (43) |
Male, n (%) | 4 (67) | 9 (60) | 13 (62) |
Median longest diameter of largest lesion, cm (range) | 3 (2–5) | 8 (2–15) | 4 (2–15) |
Median circulating lymphocytes, 109/L (range) | 1.7 (0.1–3.8) | 1.1 (0.4–83.9) | 1.2 (0.1–83.9) |
Median creatinine clearance, mL/min (range) | 108 (72–140) | 57 (36–94) | 70 (36–140) |
Median number of prior therapies, n (range) | 2 (1–2) | 2 (1–4) | 2 (1–4) |