Fig. 1

The study design and correlation analyses between mRNA and proteome data. a Study workflow. b Distribution of correlations for mRNA-protein pairs across 74 samples (the red dashed line indicates the median value of mRNA-protein correlations). c GSEA enrichment analysis showed pathways with positive mRNA-protein correlations (Kolmogorov–Smirnov test, Benjamini–Hochberg adjusted P < 0.01. The mean correlation was shown in parentheses, which was followed by the adjusted P value. Individual proteins in each pathway were represented as bars on the x axis, in which golden bars indicate positive correlations, and purple ones indicate negative correlations). d Co-expression networks of protein and mRNA data respectively, based on Joint Random Forest (JRF) method