From: Contradictory roles of lipid metabolism in immune response within the tumor microenvironment
Source | Key enzymes | Category | Functions | Regulators | References |
---|---|---|---|---|---|
Exogenous | CD36 FATP MAGT DAGT LDLR | Fatty acid | FAO | ACS CPT1 | |
Endogenous | ACLY ACC FASN | Regulate signaling pathways and gene transcription | PPARs SREBP-1 | ||
Physical processes and component formation | Â | ||||
Exogenous | LDLR VLDLR | CE synthesis | ACAT | ||
Endogenous | HMGCR | Cholesterol | Cholesterol efflux | ABCA1 ABCG1 | Â |
Regulate signaling pathways and gene transcription | LXRs | ||||
Physical process and component formation | Â | ||||
Endogenous | Â | Lipid droplet | Store energy | ATGL HSL MAGL LAL | |
Keep lipid metabolism balance |