Fig. 1

LncRNA Snhg6 promotes Mo-MDSCs but not affects the differentiation of PMN-MDSCs. a LncRNA Snhg6 expression in Tu-MDSCs compared with SP-MDSCs measured by qRT-PCR. b, c Typical flow cytometry of CD11b⁺ Gr-1⁺ MDSCs. d–g The percentage and absolute number of CD11b⁺ Gr-1⁺ MDSCs by statistical analyses. h, i Typical flow cytometry and the percentage of CD11b⁺ Ly6G⁺ Ly6C^low PMN-MDSCs and CD11b⁺ Ly6G⁻ Ly6C^high Mo-MDSCs after downregulating the expression of lncRNA Snhg6. j, k Typical flow cytometry and percentage of CD11b⁺ Ly6G⁺ Ly6C^low PMN-MDSCs and CD11b⁺ Ly6G⁻ Ly6C^high Mo-MDSCs after increasing the expression of lncRNA Snhg6. Each expression had three replicates, ns: no significance; * p < 0.05; ** p < 0.01