From: STAT proteins: a kaleidoscope of canonical and non-canonical functions in immunity and cancer
STAT protein | Major functions | References |
---|---|---|
STAT1 | Immunity against viral and bacterial infection | |
STAT2 | Immunity against viral and bacterial infection | |
STAT3 | Regulation of innate immunity and inflammation, stem cell maintenance, cell metabolism | |
STAT4 | Development and function of adaptive and innate immune cells | |
STAT5A/B | Development of multiple blood and immune cell lineages | [13] |
STAT6 | Regulation of innate and humoral immunity |