Fig. 1

A Examples of GSK3β staining intensity in soft tissue sarcomas. GSK3β was evaluated semi-quantitatively including percentage (0–100%) and intensity (0 = null, 1 = low, 2 = moderate, 3 = strong). B Kaplan–Meier curves of metastases-free survival in 402 patients with soft tissue sarcomas according to GSK3β expression (blue line: low expression, < 50% of tumor cells n = 296; green line: high expression: ≥ 50% of tumor cells n = 106). C Kaplan–Meier curves of metastases-free survival in 268 patients with grade 3 soft tissue sarcomas according to GSK3β expression (blue line: low expression, < 50% of tumor cells n = 200; green line: high expression: ≥ 50% of tumor cells n = 68)