Total (n = 449) | No AOE (n = 371) | Any AOE (n = 78) | Serious AOE (n = 74) | |
---|---|---|---|---|
Baseline concomitant medications | ||||
Antihypertensives | 86 (19) | 63 (17) | 23 (29) | 22 (30) |
Acetylsalicylic acid | 39 (9) | 23 (6) | 16 (21) | 15 (20) |
Platelet aggregation inhibitors | 38 (8) | 22 (6) | 16 (21) | 15 (20) |
Anti-diabetic agents | 24 (5) | 13 (4) | 11 (14) | 10 (14) |
Lipid-modifying agents | 22 (5) | 16 (4) | 6 (8) | 6 (8) |
Anticoagulants | 15 (3) | 13 (4) | 2 (3) | 2 (3) |
Concomitant medication use at any time | ||||
Antihypertensives | 233 (52) | 181 (49) | 52 (67) | 50 (68) |
Acetylsalicylic acid | 125 (28) | 92 (25) | 33 (42) | 33 (45) |
Platelet aggregation inhibitors | 122 (27) | 85 (23) | 37 (47) | 37 (50) |
Anticoagulants | 58 (13) | 50 (13) | 8 (10) | 8 (11) |
Lipid-modifying agents | 51(11) | 39 (11) | 12 (15) | 12 (16) |
Anti-diabetic agents | 45 (10) | 26 (7) | 19 (24) | 18 (24) |