Skip to main content
Fig. 7 | Journal of Hematology & Oncology

Fig. 7

From: Treatment with soluble CD24 attenuates COVID-19-associated systemic immunopathology

Fig. 7

Patients with severe COVID-19 that require an ICU treatment display increased correlation and connectivity of the systemic cytokine network. We analyzed correlation (A) and connectivity (B) between circulating cytokines and chemokines in COVID-19 patients that either required (ICU patients), or did not require an ICU treatment (non-ICU patients). Cytokine measurements were obtained from previously published dataset [40]. Analysis was performed as described in Fig. 6. A density plot constructed based on connectivity between plasma cytokines is shown in C. D shows an association between the severity of COVID-19 infection and the degree of the connectivity between plasma cytokines with severe UCU cases displaying higher degree of connectivity. p-value was calculated using Wilcoxon Rank sum

Back to article page