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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: A four-stage model for murine natural killer cell development in vivo

Fig. 2

NK cell stage alternation in MCMV infection and B16F10 tumor models. For the viral infection model, C57BL/6 J mice were infected with an intraperitoneal injection of 2.5 × 104 PFU MCMV. For the tumor-bearing model, B16F10 cells (1 × 105) were injected intravenously into C57BL/6 J mice. AF The percentages, absolute number, and representative dot plots of four stages of NK cells in BM from MCMV infection model (AC, n = 5 per group) and B16F10 tumor model (DF, n = 3–5 per group). G The new four-stage model for in vivo development of murine NK cells in the BM. Data are shown as mean ± SD and were analyzed by two-way ANOVA with Šídák post-test (A, B, D, E). Data are representative of at least three independent experiments. **P < 0.01; ***P < 0.001

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