Fig. 5

Subgrouping of DCC and ICC with combined biomarkers. A, D, G, J, M, P, S, V Kaplan–Meier curves of overall survival of patients whose tumors are subgrouped by higher density versus lower density of two immune cell subtypes including PD-L1⁺ or PD-L1⁻, M1 or M2 TAM and/or Treg as indicated. B, E, H, K, N, Q, T, W Schematic recombination of subgroups defined by two immune cell subtypes. C, F, I, L, O, R, U, X Kaplan–Meier curves of overall survival of patients whose tumors are re-grouped by following the schematic recombination of subgroups defined by two immune cell subtypes as indicated