Table 1 Risk of 28-day post-vaccination AESI in vaccinated and unvaccinated patients with cancer after propensity score matching
Cohorts | BNT162b2 | CoronaVac | ||||||
|---|---|---|---|---|---|---|---|---|
Events/follow-up time (person-days)/incidence (per 10,000 person-days) | Hazard ratioa (95% CI) | P value | Events/follow-up time (person-days)/incidence (per 10,000 person-days) | Hazard ratio (95% CI) | P value | |||
Unvaccinated (N = 4175) | Vaccinated (N = 4175) | Unvaccinated (N = 3352) | Vaccinated (N = 3352) | |||||
Active cancer | ||||||||
All | 10/97586/1.02 | 3/97588/0.31 | 0.30 (0.08–1.09) | 0.07 | 7/79150/0.88 | 1/78204/0.13 | 0.14 (0.02–1.18) | 0.07 |
 Male | 7/24853/2.82 | 1/23796/0.42 | 0.15 (0.02–1.22) | 0.08 | 3/23137/1.30 | 1/22894/0.44 | – | – |
 Female | 3/72733/0.41 | 2/73792/0.27 | 0.65 (0.11–3.92) | 0.64 | 4/56013/0.71 | 0/55310/0 | – | – |
 Age < 60 years | 1/50970/0.20 | 2/51891/0.39 | – | – | 1/33853/0.30 | 1/33410/0.30 | – | – |
 Age ≥ 60 year | 9/46616/1.93 | 1/45697/0.22 | 0.11 (0.01–0.90) |  < 0.05 | 6/45297/1.32 | 0/44794/0 | – | – |
 Solid tumor | 8/90350/0.89 | 3/90634/0.33 | 0.37 (0.10–1.41) | 0.15 | 7/75622/0.93 | 1/74229/0.13 | 0.15 (0.02–1.19) | 0.07 |
 Hematological malignancy | 2/7236/2.76 | 0/6954/0 | – | – | 0/3528/0 | 0/3975/0 | – | – |
|  | Unvaccinated (N = 9006) | Vaccinated (N = 9006) |  |  | Unvaccinated (N = 8929) | Vaccinated (N = 8929) |  |  |
|---|---|---|---|---|---|---|---|---|
History of cancer | ||||||||
All | 19/213182/0.89 | 12/216640/0.55 | 0.62 (0.30–1.28) | 0.20 | 20/214652/0.93 | 9/213033/0.42 | 0.45 (0.21–1.00) |  < 0.05 |
 Male | 13/94638/1.37 | 4/96765/0.41 | 0.30 (0.10–0.92) |  < 0.05 | 14/107447/1.30 | 8/106183/0.75 | 0.58 (0.24–1.38) | 0.22 |
 Female | 6/118544/0.51 | 8/119875/0.67 | 1.32 (0.46–3.81) | 0.61 | 6/107205/0.56 | 1/106850/0.09 | 0.17 (0.02–1.39) | 0.10 |
 Age < 60 years | 7/99158/0.71 | 4/99283/0.40 | 0.57 (0.17–1.96) | 0.37 | 5/77057/0.65 | 0/74134/0 | – | – |
 Age ≥ 60 years | 12/114024/1.05 | 8/117357/0.68 | 0.65 (0.27–1.60) | 0.35 | 15/137595/1.09 | 9/138899/0.65 | 0.59 (0.26–1.36) | 0.22 |
 Solid tumor | 18/197988/0.91 | 10/202083/0.49 | 0.55 (0.25–1.18) | 0.12 | 19/203168/0.94 | 8/201881/0.40 | 0.42 (0.19–0.97) |  < 0.05 |
 Hematological malignancy | 1/15194/0.66 | 2/14557/1.37 | – | – | 1/11484/0.87 | 1/11152/0.90 | – | – |