Fig. 7
From: Integrated proteogenomic characterization of urothelial carcinoma of the bladder
Clinical outcomes associated with proteomics and phosphoproteomic profiles. A Heatmap showing the correlation between modules obtained from WGCNA analysis and clinical outcomes. B Enrichment pathway of different modules (Wilcoxon rank-sum test, p < 0.05). The dot plot on the left summarizes ssGSEA pathway scores based on proteomics data among samples with different histological variation statuses. C The ssGSEA pathway analysis of different histological variations (Wilcoxon rank-sum test, p < 0.05). D Signature proteins of pathways associated with different histological variations (Wilcoxon rank-sum test, p < 0.05). E Evaluation of kinase activities in tumors across different histological variation via KSEA. F–H Diagram showing kinase–substrate associations among papillary, NOS, and differentiation variation tumors