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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: Reshaping the systemic tumor immune environment (STIE) and tumor immune microenvironment (TIME) to enhance immunotherapy efficacy in solid tumors

Fig. 2

The functions of immune regulator TGF-β1 on TIME and STIE. TGF-β1 has dual roles in the TIME and STIE. TGF-β1 has multiple impacts on different kinds of immune cells. The detail functions of TGF-β1 are shown by different arrows (Solid arrow: stimulation, Dashed arrow: possible stimulation, Vertical-horizontal line: suppression). TGF-β1: Transforming growth factor-beta1; TIME: Tumor Immune Microenvironment; STIE: Systemic Tumor Immune Environment

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Journal of Hematology & Oncology

ISSN: 1756-8722

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