Table 1 Efficacy in evaluable patients
Eltanexor (10 mg) N = 5 | Eltanexor (20 mg) N = 10 | Total N = 15 | |
|---|---|---|---|
ORR, n (%) | 3 (60) | 5 (50) | 8 (53.3) |
MCR, n (%) | 3 (60) | 4 (40) | 7 (46.7) |
HI, n (%) | 1 (20) | 2 (20) | 3 (20) |
HI with MCR | 1 (20) | 1 (10) | 2 (13.3) |
HI with SD | 0 | 1 (10) | 1 (6.7) |
SD, n (%) | 2 (40) | 2 (20) | 4 (26.7) |
PD, n (%) | 0 | 3 (30) | 3 (20) |
Treatment duration, weeks | 15 | 12 | 13 |
Median time to response, weeks | 8.1 | 9.1 | 8.4 |
Median duration of response, weeks (95% CI) | 7.86 (NE, NE) | 25.29 (13.12, NE) | 19.21 |