Table 2 ROS-responsive building blocks for cancer treatment
Type of chemical bond | Nanoplatform | Tumor model | Therapy strategies | Refs. |
|---|---|---|---|---|
Thioketal linker | Polyprodrug NPDOX/Cy | Breast cancer | Chemotherapy | [493] |
Phenylboronate ester | G5.NHAc-Toy@TF nanocomplexes | Breast cancer | Chemotherapy, CDT | [494] |
| Â | pPBA(TL)-MN | Breast cancer | Immunotherapy | [495] |
Bilirubin | Dox@bt-BRNPs | Cervical carcinoma | Chemotherapy | [496] |
| Â | TH-302@BR-Chitosan NPs | Cervical carcinoma | Chemotherapy PTT | [497] |
Gallic acid-ferrous nanocomplex | BSO/GA–Fe(II)@ liposome | Breast cancer | CDT | [119] |
Ru nanoparticle | HA-Ru NAs | Breast cancer | PTT, PDT, CDT | [498] |
FePt nanoparticle | FePt/MoS2-FA nanocomposites | Breast cancer | Immunotherapy, PTT | [499] |
Manganese ferrite nanoparticle (MFN) | MFMSN-Ce6 | Melanoma | SDT | [500] |
Horseradish peroxidase | Lipo@HRP&ABTS | Breast cancer | PTT | [501] |
| Â | PEG-TiO1+x NRs | Breast cancer | SDT, CDT | [502] |
Catalase | CAT@Pt (IV)-liposome | Breast cancer | Chemotherapy, RT | [133] |
| Â | CAT@HA-HMME NPs | Colorectal cancer | SDT | [503] |
Bis(3,4,6-trichloro-2-(pentyloxycarbonyl) phenyl) oxalate | POCL | Cervical carcinoma | PDT | [504] |