Fig. 3
From: Targeting macrophages in hematological malignancies: recent advances and future directions
Anti-tumor mechanisms of blocking CD47/SIRPα interaction: through blocking the CD47/SIRPα interaction, anti-tumor effects were induced via direct cancer-killing effects, antibody-dependent cellular phagocytosis (ADCP), antigen presentation and T cell immune responses, antibody-dependent cytotoxicity (ADCC), and complement-dependent cytotoxicity (CDC)