Fig. 3From: Somatic copy number alteration and fragmentation analysis in circulating tumor DNA for cancer screening and treatment monitoring in colorectal cancer patientsPerformance of ML classifiers based on global and regional fragmentation as well as a meta-learner. Performance was assessed over 100 bootstrapping iterations with fivefold cross validation A using the best performing model out of four classifiers for each iteration and B only a support vector machine over all iterations. C The three final classifiers detect ctDNA in CRC patients with high sensitivityBack to article page