Fig. 2From: Liquid biopsy: current technology and clinical applicationsAdvantages and disadvantages of liquid versus tissue biopsy. Liquid biopsies are non-invasive, less expensive, can assess multiple tumor sites, and can be obtained serially. Low tumor DNA shed, CHIP, and reproducibility issues may limit usage. CTC isolation can also be technically challenging. Image created with help of Biorender.com. CHIP: clonal hematopoiesis of indeterminate potential, CTCs: circulating tumor cellsBack to article page