Fig. 2

How glycolytic metabolism supports CRLM. Colorectal cancer liver metastasis (CRLM) relies on a small proportion of CRC cells which acquire a series of features including epithelial-to-mesenchymal transition (EMT), cell migration through extracellular matrix (ECM), stemness and redox homeostasis. Aerobic glycolysis could support these processes to accelerate metastasis. Arrows indicate positive modulations or transitions, while blunt ends indicate negative modulations