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Fig. 5 | Journal of Hematology & Oncology

Fig. 5

From: Small-molecule inhibitors, immune checkpoint inhibitors, and more: FDA-approved novel therapeutic drugs for solid tumors from 1991 to 2021

Fig. 5

FDA-approved therapeutic drugs for gastrointestinal cancers. a Distribution of therapeutic drugs for gastrointestinal cancers during the past 31 years (adapted from [865, 866]). b Photosensitizer. c VEGFR2-directed mAb. d Multitarget TKI and PDGFR inhibitors. e Somatostatin receptor-targeted radiopharmaceutical. f FGFR inhibitors. g DNA synthesis inhibitor. h DNA topoisomerase inhibitor. i Organoplatinum alkylating agent. j EGFR‑directed mAb. k VEGF‑A-directed mAb. l Soluble receptor decoy that binds VEGF-A, VEGF-B, and PlGF. m Multitarget TKI. n Thymidine phosphorylase inhibitor plus nucleoside metabolic inhibitor

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