Fig. 8From: Small-molecule inhibitors, immune checkpoint inhibitors, and more: FDA-approved novel therapeutic drugs for solid tumors from 1991 to 2021FDA-approved therapeutic drugs for melanoma and other skin cancers. a Distribution of therapeutic drugs for melanoma and other skin cancers during the past 31 years (adapted from [868]). b BRAF inhibitors. c MEK inhibitors. d CTLA4‑directed mAb. e PD1-directed mAbs. f Smoothened inhibitors. g PDL1-directed mAb. h PD1-directed mAbBack to article page