Fig. 7

Single-cell transcriptome atlas of the TME after the combination therapy in EMT-6 model. a Uniform manifold approximation and projection (UMAP) plot for immune cells. b UMAP plot for the treatment group-specific distribution of immune cells. c Heatmap showing cluster-specific gene profiles. d Histogram representing the proportion of clusters in each group. e Heatmap depicting the results of GSEA using Hallmark gene sets. f T-distributed stochastic neighbor embedding (t-SNE) plots for tumor-infiltrating T cells. g t-SNE plots for the treatment group-specific distribution of T cells. h Violin plots showing T cell subcluster-specific gene profiles. i Heatmap depicting the results of GSEA using KEGG gene sets for T cell subclusters. j Histogram representing the proportion of T cell subclusters in each group