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Table 2 Clinical–pathological characteristics of MED cohort

From: miRNome profiling of lung cancer metastases revealed a key role for miRNA-PD-L1 axis in the modulation of chemotherapy response

 

ALL (n = 52)

pN0 (n = 10)

pN2 (n = 32)

pN1 (n = 10)

Age

 Median (Q1;Q3)

62.12 (59.18; 68.24)

62.05 (59.81; 70.32)

61.32 (58.82; 66.97)

62.95 (59.86; 66.32)

Gender

 Female

15 (28.8%)

3 (30%)

9 (28.1%)

3 (30%)

 Male

37 (71.2%)

7 (70%)

23 (71.9%)

7 (70%)

Histology

 LUAD

30 (57.7%)

4 (40%)

22 (68.7%)

4 (40%)

 LUSC

19 (36.5%)

4 (40%)

9 (28.1%)

6 (60%)

 NSCLC

3 (5.8%)

2 (20%)

1 (3.1%)

0 (0%)

Stage

 IIIA

46 (88.5%)

8 (80%)

29 (90.6%)

9 (90%)

 IIIB

6 (11.5%)

2 (20%)

3 (9.4%)

1 (10%)

NACT regimen

 CDDP + ALIMTA

6 (11.5%)

0 (0%)

5 (15.6%)

1 (10%)

 CDDP + GEM

41 (78.8%)

9 (90%)

25 (78.1%)

7 (70%)

 CDDP + TAXOTERE

1 (1.9%)

0 (0%)

1 (3.1%)

0 (0%)

 CDDP + VNR

4 (7.7%)

1 (10%)

0 (0%)

2 (20%)

 VNR + GEM

1 (1.9)

0 (0%)

1 (3.1%)

0 (0%)

Number of NACT cycles

 2–3 cycles

42 (80.8%)

9 (90%)

24 (75%)

9 (90%)

 4–5 cycles

9 (17.3%)

1 (10%)

7 (25%)

1 (10%)

  1. Percentages could not add up to 100% due to rounding
  2. LUAD lung adenocarcinoma, LUSC lung squamous cell carcinoma, NSCLC other non-small cell lung subtypes, NACT neoadjuvant chemotherapy, CDDP cisplatin, GEM gemcitabine, CBDCA carboplatin, VNR vinorelbine, NA no available data