Skip to main content
Fig. 4 | Journal of Hematology & Oncology

Fig. 4

From: APOBEC3-mediated mutagenesis in cancer: causes, clinical significance and therapeutic potential

Fig. 4

Effects of APOBEC3-induced factors on prognosis varies  among cancer types. APOBEC3s can affect tumorigenesis through mutagenic and non-mutagenic pathways, which may have opposing effects on disease course. The relative strength of these effects may determine the prognostic significance of APOBEC3s, explaining the varied clinical impact of APOBEC3s by cancer type (Table 5). Examples for specific cancer types are shown.

Back to article page