Fig. 6From: APOBEC3-mediated mutagenesis in cancer: causes, clinical significance and therapeutic potentialCauses, consequences, and clinical aspects of APOBEC3-mediated mutagenesis in cancer. A variety of exogenous and endogenous factors can induce APOBEC3s, which can then impact cancer growth through mutagenic and non-mutagenic pathways. These APOBEC3-mediated effects may shape clinical outcomes and be relevant in both the current and future therapeutic landscapes.Back to article page