Table 3 Non-hematologic toxicities
Toxicity | Grade 3, N (%) | Grade 4, N (%) | Grade 5, N (%) |
|---|---|---|---|
Infections-related and unrelated | 49 (45) | 17 (15) | 7 (6) |
Hyperglycemia | 21 (19) | 4 (4) | 0 |
Pain (back, bone, abdominal, joint, muscle) | 19 (17) | 0 | 0 |
Hemorrhage | 14 (13) | 1 (1) | 2 (2) |
Increased liver function tests | 13 (12) | 2 (2) | 0 |
Hypokalemia | 11 (10) | 4 (4) | 0 |
Increased bilirubin | 10 (9) | 2 (2) | 0 |
Cardiac | 10 (9) | 0 | 1 (1) |
Neurotoxicities | 9 (8) | 2 (2) | 0 |
Headache | 9 (8) | 0 | 0 |
Fatigue | 5 (5) | 0 | 0 |
Constipation | 5 (5) | 0 | 0 |
Mucositis | 5 (5) | 0 | 0 |
Hepatic sinusoidal obstruction syndrome | 2 (2) | 0 | 2 (2) (1 pre SCT, 1 post SCT) |
Nausea | 3 (3) | 1 (1) | 0 |
Hyponatremia | 2 (2) | 1 (1) | 0 |
Thrombosis | 3 (3) | 0 | 0 |
Generalized muscle weakness | 3 (3) | 0 | 0 |
Hypoalbuminemia | 3 (3) | 0 | 0 |
Hypophosphatemia | 3 (3) | 0 | 0 |
Diarrhea | 2 (2) | 0 | 0 |
Neuropathy | 2 (2) | 0 | 0 |
Pancreatitis | 2 (2) | 0 | 0 |
Acute kidney injury | 2 (2) | 0 | 0 |
Hypercalcemia | 2 (2) | 0 | 0 |
Hypocalcemia | 2 (2) | 0 | 0 |