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Table 1 Transforming potential of BCR-ABL-GFP vs. BCR-ABL-GFP + N17 H-Ras

From: Effect of Ras Inhibition in Hematopoiesis and BCR/ABL Leukemogenesis

Cells

Assays

BCR-ABL-GFP*

BCR-ABL-GFP + N17 H-Ras*

GFP vector*

NIH 3T3

# of foci

117 +/- 16†

11 +/- 2

-

Bone marrow

# of colonies

16 +/- 0.6

0.33 +/- 0.33

-

  1. * Retroviral titers were matched.
  2. †Results are shown as the mean ± SD of three independent experiments.
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Journal of Hematology & Oncology

ISSN: 1756-8722

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