Figure 3

Hematoxylin and eosin (HE) staining and immunohistochemistry analyses of bone marrow (BM), spleen, and lymph nodes (LNs) from autopsy. HE staining of BM showed hypercellularity, and increased blasts. These blasts expressed MPO, whereas the population of lymphocytes was small and there was almost no staining for EBER in the BM. The spleen tissue also showed diffuse infiltration of myeloblasts, and rare EBER-positive lymphocytes. In contrast, leukemic cells and EBER-positive lymphocytes were seen in the LNs. (magnification: ×800).