Agents | Mechanism of action | Administration | Main side effects | State |
---|---|---|---|---|
Vorapaxar | a non-peptide competitivePAR1 thrombin receptor antagonist with a high affinity and low molecular weight | oral | bleeding | unapproved |
Atopaxar | PAR1 antagonist inhibiting thrombin-mediated platelet aggregation | oral | bleeding | unapproved |