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Table 1 Patient demographics and treatment outcomes by regimen

From: Treatment outcome and prognostic factor analysis in transplant-eligible Chinese myeloma patients receiving bortezomib-based induction regimens including the staged approach, PAD or VTD

 

Staged Approach N = 25

PAD N = 31

VTD N = 35

p-value

(A) Demographics

Mean age

52.44

53.42

55.71

0.18

Male gender

17 (68 %)

15 (48.4 %)

18 (51.4 %)

0.296

Isotype

   

0.504

 G

12

15

13

 

 L

6

8

11

 

 A

4

2

9

 

 D

2

4

1

 

 NS

1

2

1

 

 ISS

   

0.83

 I

7 (28 %)

11 (35.5 %)

11 (32.4 %)

 

 II

7 (28 %)

5 (16.1 %)

6 (17.6 %)

 

 III

11 (44 %)

14 (48.4 %)

17 (50 %)

 

High-risk Karyotype

3/5 (60 %)

2/6 (33.3 %)

4/12 (25 %)

0.35

(B) Outcomes

CR/nCR post-induction

6 (24 %)

13 (41.9 %)

15 (42.9 %)

0.268

≥VGPR post-induction

14 (56 %)

26 (83.9 %)

26 (74.3 %)

0.064

CR/nCR post-ASCT

15 (62.5 %)

23 (74.2 %)

19 (63.3 %)

0.569

≥VGPR post-ASCT

19 (79.2 %)

29 (93.5 %)

27 (90 %)

0.242

5-year OS

59.80 %

78.70 %

73.80 %

0.661

5-year EFS

36.30 %

52.50 %

69.80 %

0.516