Figure 1

Distribution of the level of telomerase activity in 24 CML samples. Telomerase activity was measured by quantitative PCR (qPCR) in triplicate in CML samples. The average of telomerase activity from three normal samples (N) is used as a control to normalize against background level. Telomerase activity in CML is expressed as the fold-increase (Y-axis) to normal samples. Error bars indicate standard errors from average telomerase activity of three measurements for each tumor sample. Half of the samples fall into the high and another half of samples fall into the low telomerase activity according to the cutoff (dashed horizontal line).