Cancer-associated fibroblasts promote the progression of endometrial cancer via the SDF-1/CXCR4 axis

Table 2 Multivariate analysis of factors associated with survival of EC patients

Variables		HR	95 % CI	Wald value	P
Age (years)	<60	1.00	0.55–3.43	0.45	0.501
Age (years)	≥60	1.37	0.55–3.43	0.45	0.501
Menopausal status	Yes	1.00	0.18–1.90	0.83	0.363
Menopausal status	No	0.58	0.18–1.90	0.83	0.363
Histologic subtype	Endometrioid	1.00	0.67–7.82	1.74	0.187
Histologic subtype	Nonendometrioid	2.29	0.67–7.82	1.74	0.187
Histopathologic grade	G1	1.00	0.55–2.97	0.31	0.578
Histopathologic grade	G2–G3	1.27	0.55–2.97	0.31	0.578
Myometrial invasion	<1/2	1.00	1.08–7.09	4.50	0.034^*
Myometrial invasion	≥1/2	2.77	1.08–7.09	4.50	0.034^*
FIGO stage	I–II	1.00	0.43–3.99	0.22	0.639
FIGO stage	III–IV	1.31	0.43–3.99	0.22	0.639
Lymph node metastasis	Yes	1.00	0.22–2.27	0.335	0.563
Lymph node metastasis	No	0.71	0.22–2.27	0.335	0.563
SDF-1α expression	Low expression	1.00	1.58–11.07	7.918	0.005^*
SDF-1α expression	High expression	4.13	1.58–11.07	7.918	0.005^*

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