Table 1 Characteristics of MDS patients (n = 58)
From: Short telomere length and its correlation with gene mutations in myelodysplastic syndrome
Characteristics | Number (%) |
|---|---|
Gender (Male/female) | 37: 21 |
Median age (year, range) | 69 (18–86) |
Age (years) | Â |
 <60 | 22 (37.9) |
 ≥60 | 36 (62.1) |
Complete blood count at bone marrow sample collection | |
 White blood cell (103/μL) | 2.6 (0.6–17.2) |
 Hemoglobin (g/dL) | 8.0 (4.4–12.2) |
 Absolute neutrophil count (/μL) | 1151 (80–11,345) |
 Platelet count (103/μL) | 74.5 (3–1029) |
Median bone marrow blast (%, range) | 2.3 (0.0–18.1) |
WHO category | |
 RCUD | 12 (20.7) |
 RARS | 4 (6.9) |
 RCMD | 13 (22.4) |
 RAEB | 20 (34.5) |
 MDS, U | 9 (15.5) |
IPSS risk groups | |
 Low | 8 (13.8) |
 Intermediate-1 | 28 (48.3) |
 Intermediate-2 | 15 (25.9) |
 High | 7 (12.1) |
Revised IPSS | |
 Very low | 4 (6.9) |
 Low | 14 (24.1) |
 Intermediate | 14 (24.1) |
 High | 14 (24.1) |
 Very High | 12 (20.7) |
Cytogenetic results | |
 Karyotype | |
  Abnormal karyotype | 32 (55.2) |
  Complex karyotype (>3 abnormalities) | 9 (15.5) |
  del(5q)/ –5 | 6 (10.5) |
  del(7q)/ –7 | 8 (14.0) |
  Trisomy 8 | 8 (14.0) |
  Abnormal 17p | 3 (5.2) |
  del(20q) | 5 (8.8) |
 Fluorescence in situ hybridization | |
  Abnormal chromosome 1a | 5 (11.1) |
  Abnormal chromosome 5b | 8 (17.4) |
  Abnormal chromosome 7b | 9 (19.6) |
  Abnormal chromosome 8b | 7 (15.2) |
  Abnormal chromosome 20b | 4 (8.7) |