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Fig. 5 | Journal of Hematology & Oncology

Fig. 5

From: Targeting of PI3K/AKT/mTOR pathway to inhibit T cell activation and prevent graft-versus-host disease development

Fig. 5

Effect of BKM120 and BEZ235 on the percentage of T cell maturation subsets. Percentage of a early effector and b naïve cells among CD4+ and CD8+ cells unstimulated or stimulated in the presence of different concentrations of BKM120 or BEZ235. Mean ± SEM of five different experiments. #p < 0.05 with respect to stimulated untreated samples (0 μM); n.s. non-significant differences with respect to stimulated untreated samples (0 μM)

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