Fig. 2

The CAR-HEMATOTOX score identifies patients at risk for severe infectious complications. A Clinical source of infection of the 51 infection events. B–C Relative distribution of infection grades for all infection subtypes (B) and bacterial infections only (C) comparing HT high versus low patients. Infection grades (1°–5°) are color-coded in shades of green with the connecting green and gray lines and percentage numbers comparing all-grade and grade ≥ 3 infections, respectively, in HT high versus low patients. Significance values were determined by Fisher’s exact test (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001). D–H Cumulative incidence curves (D0–90) by HT score for any-grade (D), grade ≥ 3 (E), as well as bacterial (F), viral (G), and fungal (H) infections. Comparison of HT risk groups was performed by log-rank test