Fig. 1

Prognostic value of PET radiomic features. Volcano plots showing PET radiomic features from (A) aph-PET and (B) car-PET scans. Radiomic features extracted from aph-PET scans did not differ significantly between patients achieving complete remission (CR) or not. In contrast, several radiomic features extracted from lymphoma manifestations on car-PET scans, such as Energy and Zone Percentage, differed significantly (P < 0.05) between the two outcome groups (CR vs. non-CR). Abbreviations: Aph-PET = pre-leukapheresis PET scan; Car-PET = pre-CAR-T cell infusion PET scan; CR = complete response; ROI = region of interest