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Table 2 Interpahse FISH results of the patients with the TEL-AML1 fusion after complete remission as MRD

From: Persistence of TEL-AML1 fusion gene as minimal residual disease has no additive prognostic value in CD 10 positive B-acute lymphoblastic leukemia: a FISH study

   Clinical course
   CR1 CR2 CR2, CNS relapse and death Resistant and death Total P
t (12; 21) at Remission (MRD) Yes 12 2 1 - 15 0.01
  No 6 9 - - 15  
Total   18 11 1 - 30  
  1. FISH was performed to the patients with a positive t(12;21) at the time of diagnosis who passed to remission; a total number of 30 patients. FISH, fluorescence in situ hybridization; CR1, first complete remission; CR2, second complete remission; CNS, involvement of the central nervous system