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Table 4 Clinical Severity Scoring of Patients with Thrombotic Thrombocytopenic Purpura/Hemolytic Uremic Syndrome[22]

From: Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS): a 24-year clinical experience with 178 patients

Score

Neurologic

Symptoms

Renal

Insufficiency

Platelet Count

(/μL)

Hemoglobin Level

(g/dL)

0

None

None

> 100,000

> 12

1

Confusion, lethargy

Cr* = 1.5–2.5

Proteinuria

Hematuria

20,000 – 100,000

9 – 12

2

Seizure, coma, focal deficits

Cr > 2.5 Dialysis

< 20,000

< 9

  1. Abbreviation: Cr: serum creatinine (in mg/dL).