Table 4 Effects of DMSO, HP-A2 and HP-G7 on proliferation, cell cycle and granulocytic differentiation in HL60 cells.
| Â | Control | DMSO | Â | HP-A2 | Â | Â | HP-G7 | Â |
|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | 10-6 M | 10-5 M | 10-4 M | 10-6 M | 10-5 M | 10-4 M |
Cell number (% of the control) | 100 | 38 ± 0.3 A | 87 ± 3.7 | 86 ± 1.6 | 87 ± 1.4 | 95 ± 1.3 | 73 ± 4.7 | 89 ± 1.3 |
G0/G1 (%) | 44.5 ± 9.1 | 58.0 ± 13.0 | 38.0 ± 2.3 | 34.0 ± 4.7 | 41.8 ± 6.1 | 43.6 ± 3.9 | 39.6 ± 6.0 | 42.5 ± 7.9 |
CD11b | 40.6 ± 1.3 | 82.2 ± 1.6 | 38.1 ± 1.2 | 40.4 ± 2.7 | 79.7 ± 3.1 | 37.7 ± 2.9 | 34.1 ± 3.9 | 57.8 ± 3.1 |
Granulocytic cells (%) | 5.5 ± 1.7 | 90.7 ± 4.3 | 13.0 ± 5.2 | 10.3 ± 3.4 | 16.5 ± 4.2 | 7.0 ± 1.3 | 10.1 ± 2.2 | 15.0 ± 2.2 |