Table 4 Drug-Related Adverse Events Reported by ≥ 15% of Patients Who Received Vorinostat Combination Therapy in the Vorinostat Clinical Trial Program (Data Cut-Off April 2008)
Adverse Event | No. (%) of Patients (N= 157) | |
|---|---|---|
| Â | All Grades | Grade 3 or 4 |
Nausea | 76 (48.4) | 8 (5.1) |
Diarrhea | 64 (40.8) | 9 (5.7) |
Fatigue | 54 (34.4) | 21 (13.4) |
Vomiting | 49 (31.2) | 6 (3.8) |
Anorexia | 32 (20.4) | 4 (2.5) |
Dehydration | 28 (17.8) | 6 (3.8) |
Thrombocytopenia | 25 (15.9) | 15 (9.6) |
Anemia | 25 (15.9) | 4 (2.5) |