Table 1 Summary of reported biological activities of garcinol

Anti-oxidant

Efficient scavenging of free radicals

Yamaguchi et al. [17]

Yamaguchi et al.[28]

Inhibition of NO and H₂O₂ production

Sang et al. [18]

Inhibition of NO and iNOS Generation

Sang et al. [19]

Inhibition of iNOS and COX-2 expression

Liao et al. [31]

Inhibition of NO accumulation

Liao et al. [30]

Anti-bacterial

Activity against methicillin-resistant Staphylococcus aureus

Iinuma et al. [23]

Rukachaisirikul et al. [22]

Efficient killing of Helicobacter pylori

Chatterjee et al. [20]

Chatterjee et al. [21]

Anti-cancer

Chemoprevention of colon tumorigenesis

Tanaka et al. [34]

Induction of caspase-3-mediated apoptosis

Pan et al. [5]

Loss of mitochondrial potential and activation of caspase-3

Matsumoto et al. [36]

Induction of apoptosis

Balasubramanyam et al. [40]

Inhibition of tongue carcinogenesis

Yoshida et al. [38]

Modulation of arachidonic acid metabolism and inhibition of STAT-1

Hong et al. [29]

Selective killing of colon cancer cells

Hong et al. [33]

Induction of apoptosis and inhibition of cell invasion

Liao et al. [35]