Figure 3

Probability of first remission duration of ALL patients in relation to the growth pattern of their leukemic blasts in SCID mice. Patients whose leukemic cells grew aggressively (newly diagnosed or relapsed, n = 23) had a poor clinical outcome. Patients whose leukemic blasts displayed either no tumor growth or an indolent growth pattern at newly diagnosis (n = 25) had a favorable clinical outcome. Patients whose leukemic blasts displayed no tumor growth or an indolent pattern at relapse (n = 18) also had a relatively favorable clinical outcome.