Table 1 Patients' molecular and clinical characteristics.
From: The frequency of NPM1 mutations in childhood acute myeloid leukemia
Patient No. | Nucleotide sequences | Sex | Age (years) | FAB Type | Karyotype | MLL rearrangement | FLT3 mutation | WBC | Blast Count in BM (%) | Survival |
|---|---|---|---|---|---|---|---|---|---|---|
Wild type | gat ctc tgg cag tgg agg aag tct ctt taa gaa aat ag | |||||||||
1 | gat ctc tgt ctg gca gtg gag gaa gtc tct tta aga aaa tag | M | 8 years | M1 | 46, xy | N | None | 23900 | 85% | Complete Remission |
2 | gat ctc tgg cag g gg agg aag c ct ctt taa gaa aat ag | F | 13 years | M2 | 46, xx t(8;21) (q22;q22) | N | FLT3/ITD | 7680 | 60% | Complete Remission |