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Table 2 Rates of complete cytogenetic response (CCyR) and major molecular response (MMR) to imatinib and nilotinib in the ENESTnd trial.

From: First-line treatment for chronic myeloid leukemia: dasatinib, nilotinib, or imatinib

 

% of patients

 

Imatinib

400 mg QD

Nilotinib

300 mg BID

Nilotinib

400 mg BID

CCyR

   

   6 months

45

67

63

   12 months

65

80

78

MMR

   

   3 months

1

9

5

   6 months

12

33

30

   9 months

18

43

38

   12 months

22

44

43

Progression to AP/BP

4

< 1

< 1

  1. AP: accelerated phase; BP: blast phase; QD: once daily.