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Table 3 IQ in high risk randomisation groups (HDM versus XRT)

From: The impact of therapy for childhood acute lymphoblastic leukaemia on intelligence quotients; results of the risk-stratified randomized central nervous system treatment trial MRC UKALL XI

  Number of patients Mean adjusted IQ*
(SD)
Difference in
means
(95% CI)
t-test
p-value
  HDM XRT HDM XRT   
FSIQ       
   3 years 45 51 98.9
(13)
94.7
(13)
4.2
(-1.1 : 9.4)
0.1
   5 years 35 34 100.5
(16)
98.2
(15)
2.3
(-5.1 : 9.8)
0.5
VIQ       
   3 years 45 51 98.9
(14)
94.9
(13)
4.0
(-1.5 : 9.5)
0.2
   5 years 35 34 100.3
(16)
98.2
(15)
2.0
(-5.5 : 9.6)
0.6
PIQ       
   3 years 45 51 99.4
(13)
95.7
(13)
3.7
(-1.5 : 8.8)
0.2
   5 years 35 34 101.0
(15)
98.4
(14)
2.7
(-4.3 : 9.7)
0.4
  1. * IQ adjusted for test by subtracting
  2. 7.15 from each WPPSI-R full IQ.
  3. 3.79 from each WPPSI-R verbal IQ.
  4. 8.74 from each WPPSI-R performance IQ.