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Table 1 Tumor and tumor thrombus size, DWI and MRP parameters at baseline and post antiangiogenic treatment

From: Magnetic resonance imaging biomarkers in hepatocellular carcinoma: association with response and circulating biomarkers after sunitinib therapy

Parameters Baseline (Median, Range) Post-sunitinib (Median, Range) P value
SIZE    
RECIST 10.00, 2.30 ~ 17.00 11.10, 1.30 ~ 25.00 0.197
m RECIST 9.94, 2.15 ~ 19.56 10.11, 2.11 ~ 18.55 0.963
Tumor thrombus(mm) 28.67, 21.87 ~ 36.63 29.81, 21.98 ~ 37.73 0.365
DWI    
HCC ADC (×10 -3 mm 2 /s) 0.88, 0.58 ~ 1.09 0.98, 0.75 ~ 1.21 <0.0001
Tumor thrombus ADC (×10 -3 mm 2 /s) 0.89, 0.60 ~ 1.14 1.02, 0.78 ~ 1.26 0.035
MRP    
HCC Ktrans (min −1 ) 2.15, 0.90 ~ 4.81 0.94, 0.57 ~ 2.30 <0.0001
Kep (min −1 ) 2.61, 1.00 ~ 41.75 1.22, 0.66 ~ 2.64 <0.0001
EVF 0.926, 0.34 ~ 1.00 0.81, 0.65 ~ 0.97 0.079
Tumor thrombus Ktrans (min −1 ) 1.89, 0.93 ~ 2.99 0.99, 0.37 ~ 1.61 0.110
Kep (min −1 ) 2.37, 1.05 ~ 4.03 1.49, 0.61 ~ 2.37 0.190
EVF 0.83, 0.70 ~ 0.98 0.66, 0.56 ~ 0.77 0.055
  1. Abbreviations: Ktrans Transfer constant; Kep Rate constant; EVF Extracellular volume fraction; ADC Apparent diffusion coefficient.