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Table 2 Distribution of patients with and without inhibitor, high and low responders, transient, slowly resolving and permanent dependent on the mutation type

From: High rate of spontaneous inhibitor clearance during the long term observation study of a single cohort of 524 haemophilia A patients not undergoing immunotolerance

N° of patients

NULL mutations inversions (Int1/22)

NULL mutations other

NOT null mutations

Unknown mutation

Total

 

N = 156

N = 79

N = 91

N = 198

N = 524

Without inhibitor

87

40

68

149

344

With inhibitor

69

39

23

49

180

Transient

17 (25%)

14 (36%)

10 (44%)

29 (59%)

70 (39%)

Slowly resolving

20 (29%)

6 (15%)

7 (30%)

14 (29%)

47 (26%)

Permanent

32 (46%)

19 (49%)

6 (26%)

6 (12%)

63 (35%)

High Responders

38 (55%)

21 (54%)

7 (30%)

13 (27%)

79 (44%)

Low Responders

31 (45%)

18 (46%)

16 (70%)

36 (73%)

101 (56%)